Cation suppression in ion chromatography

Cation suppression in ion chromatography

Chemistry & Biochemistry / Water & Beverages

March 21, 2016

Trace analysis of cations, amines, and transition metals is possible with or without suppression. However, some applications require particularly high sensitivity of the analysis. This can only be achieved by sequential suppression, as suppression considerably lowers the detection limits for the analytes. Such analyses are common, for instance, in power plant applications or in pharmaceutical applications. Moreover, there are a number of norms and standards that request cation analysis with suppression. In short, suppression reduces background conductivity to a minimum and decreases baseline noise. Both effects together improve the signal-to-noise ratio and increase the sensitivity of the measuring system. Thus, whenever the quantification of very low concentrations of cations is required, analysis with sequential suppression is the method of choice.

The Metrohm Suppressor Module

The patented Metrohm Suppressor Module (MSM) is a very effective and highly robust solution when suppression is needed. The heart of the MSM is a small rotor that contains three cartridges, filled with anion exchange resin. While the first cartridge is being used for suppression, the second one is regenerated. At the same time, the third cartridge is rinsed to remove any residual regenerant. As the cartridges are rotated one step before each new injection, there is always a freshly regenerated suppressor cartridge ready for the next injection.

STREAM – the green way of suppression

STREAM (Suppressor Treatment Re-using Eluent After Measurement) adds even more benefits to the suppression technique described. STREAM refers to a process whereby, instead of simply disposing of the suppressed eluent after detection, it is used to rinse the regenerated suppressor unit. Moreover, the use of the STREAM technique results in considerably lower consumption of regenerant.

STREAM enables users to perform sustainable, «green chemistry» while saving on operating costs. Moreover, longer system run times frees up more time for the user to perform other tasks in the laboratory.

BRCA Tumor MASTR Plus Product launch

BRCA Tumor MASTR Plus Product launch

Chemistry & Biochemistry / Water & Beverages

Multiplicom is pleased to announce the release of the BRCA Tumor MASTR Plus molecular assay, research use only, for identification of SNVs in the coding region of BRCA1 and BRCA2 in various types of solid tumors.

June 17, 2015 More +
Improve DNA extraction from diverse soil environments

Improve DNA extraction from diverse soil environments

Chemistry & Biochemistry / Water & Beverages

It is well known that the gut microbiota contributes to health and disease. Many studies have demonstrated that external factors such as diet, geographical location and host genetics are key contributors. However, the relative contribution of these factors in shaping the gut microbiota is unclear, likely due to large interindividual variation.

February 28, 2017 More +
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